The Arizona Cardinals' most loaded injury report of the season doesn't come at the best time.
Heading into what may be their most physical, personal matchup of the season to date, the Cards will be without several key pieces on offense or defense Sunday at NFC West division rival St. Louis.
We already knew starting running back Chris Johnson, who suffered a fractured tibia during last weekend's win at the 49ers, will be out Sunday and all the way up until the Super Bowl after he was placed on injured reserve Tuesday.
But in addition, No. 2 RB Andre Ellington will also miss Sunday's game with a turf toe injury, meaning rookie David Johnson should get his first career start in the Cards' backfield. Also, wide receiver Michael Floyd is questionable with a hamstring injury.
See also: Three reasons the Cardinals will be OK without Chris Johnson
On the other side of the ball, defensive tackle Frostee Rucker will miss his second straight game with an ankle injury, and cornerback Jerraud Powers will be sidelined with a calf injury.
The Cardinals will look to avenge their only home loss of the season -- and the Rams' only road win of the season -- on Sunday. St. Louis upset the Cards 24-22 in Glendale in Week 4 to hand Arizona its first loss of the year.
Final #AZCardinals injury report for #AZvsSTL. No surprises. pic.twitter.com/IhNOJjehe8
— Darren Urban (@Cardschatter) December 4, 2015