Officials are investigating a deadly rollover crash on Interstate 10 west of Tonopah.
The Arizona Department of Public Safety said two people have been confirmed dead at the scene. Two other people have serious injuries.
Only one vehicle was involved in the crash.
DPS spokesman Bart Graves said the vehicle was traveling eastbound on I-10 when, "for an unknown reason," went off to the left, overcorrected, and rolled.
The two killed are a man and a woman. Those hospitalized were taken to Abrazo Medical Center West Valley.
The highway was closed, but has since reopened.