Arizona Cardinals look to regain confidence in battle against Buffalo Bills

GLENDALE, AZ - The Arizona Cardinals and the Buffalo Bills could each use a win Sunday to boost their confidence after the Cardinals fell to the St. Louis Rams and the Bills were crushed by the San Francisco 49ers in week five.

But injuries plague the Cardinals team, both offensively and defensively.

The Cardinals lost running back Beanie Wells early in the season. The earliest he could return would be in late November. Then Ryan Williams suffered a season-ending injury to his shoulder against the Rams in week five.

You should expect LaRod Stephens-Howling, William Powell and Alfonso Smith to share the rushing duties in week six. (The three have combined for 10 yards on 15 carries this season.)

A rising problem for the Cardinals has been quarterback sacks. Kevin Kolb was sacked nine times against the Rams and eight times against the Dolphins in week four, something head coach Ken Whisenhunt said is a problem that doesn't just stem from the offensive line. However, they could benefit from a Buffalo team that has been outscored 97-31 in the last two weeks.

Heading into week six, Kolb has completed 95 of 157 passes for 1,041 yards and seven touchdowns. Bills quarterback Ryan Fitzpatrick has similar statistics, completing 88 of 151 passes for 1,057 yards and 12 touchdowns.

But Buffalo's defensive end Mark Anderson will have surgery on his left knee and will be out indefinitely, so that leaves 10-year veteran Chris Kelsay with the starting duties.

Prediction: Bills 21, Cardinals 24

By the way, in 2008, Fitzgerald had two touchdown receptions against the Bills in their 41-17 win.

The game airs at 1 p.m. on CBS5.