Owen Wilson attends the UK premiere of 'Marley And Me' at the VUE west End, Leicester Square on March 2, 2009 in London, England. (Gareth Cattermole, Getty Images)

Owen Wilson has signed on to be the voice of cartoon dog Marmaduke in a new film.

The actor will join William H. Macy, Fergie, Steve Coogan and Wayans brothers Damon and Marlon in Fox’s CGI/live-action movie adaptation of the 55-year-old comic, according to The Hollywood Reporter.

It won't be the first time Wilson's voice has been the star of a movie. Wilson played Lightning McQueen in hit 2006 animated movie Cars and he portrays Coach Skip in pal Wes Anderson's upcoming animated tale Fantastic Mr. Fox.