Slideshow

Actor Johnny Depp arrives at the European Film Premiere of 'Public Enemies' at The Empire Leicester Square on June 29, 2009 in London, England. (Gareth Cattermole, Getty Images)

Johnny Depp is eyeing the chance to go traveling with Angelina Jolie. He is in talks to step into Tom Cruise's shoes in The Tourist.

Jolie stepped up to replace Charlize Theron in the remake of 2005 French thriller Anthony Zimmer after the South African beauty was forced to drop out.

Cruise was also slated to star, but pulled out of his part to team up with Vanilla Sky co-star Cameron Diaz in a new movie.

Aussie actor Sam Worthington was reported to have accepted the role, but has since dropped out, and Depp has now been lined up for the lead part, according to Variety.

The film tells the tale of a female agent on the hunt for an elusive ex-boyfriend, who becomes a wanted man.